Background: Patients with triple-vessel ischemic heart disease and reduced left ventricular ejection fraction (LVEF) present a high-risk surgical population. Off-pump coronary artery bypass grafting (OPCAB) has been proposed as a safe revascularization strategy with potential for functional recovery. This study aimed to evaluate changes in LVEF and perioperative outcomes following OPCAB in patients stratified by baseline LVEF. Methods: This descriptive cross-sectional study was conducted in the Department of Cardiac Surgery, Bangladesh Medical University, Dhaka, from September 2024 to August 2025. A total of 120 patients with angiographically confirmed triple-vessel ischemic heart disease and viable myocardium assessed by Dobutamine stress echocardiography underwent OPCAB. Patients were divided into four groups according to baseline LVEF: Group A (20–30%), Group B (31–40%), Group C (41–50%) and Group D (>51%). LVEF was measured by transthoracic echocardiography preoperatively, on the 7th postoperative day, at 1 month and at 3 months. Results: The mean age of the study population was 55.8 ± 7.0 years, with males comprising 68%. Progressive improvement in LVEF was observed in all groups. Group A showed the largest relative gain (25 ± 3% to 36 ± 5% at 3 months), with 83% achieving ≥5% improvement and 50% achieving ≥10%. Overall, 64% of patients improved by ≥5% and 28% by ≥10%. Perioperative mortality was low (0.8%), while postoperative myocardial infarction (3.3%), arrhythmias (11.7%), prolonged ICU stay (18.3%) and wound infection (3.3%) were observed, particularly among patients with lower baseline EF. Conclusion: OPCAB in patients with triple-vessel ischemic heart disease and viable myocardium is associated with significant improvement in LVEF, particularly in those with lower baseline EF and carries a low incidence of perioperative complications.
| Published in | Cardiology and Cardiovascular Research (Volume 9, Issue 4) |
| DOI | 10.11648/j.ccr.20250904.13 |
| Page(s) | 131-136 |
| Creative Commons |
This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited. |
| Copyright |
Copyright © The Author(s), 2025. Published by Science Publishing Group |
Off-pump Coronary Artery Bypass Grafting, Left Ventricular Ejection Fraction, Ischemic Heart Disease, Myocardial Viability
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APA Style
Alauddin, M., Sunny, M. S. A., Rahman, K. M. A., Hossain, N., Ahmed, M., et al. (2025). Effect on Left Ventricular Ejection Fraction After off Pump Coronary Artery Bypass Grafting of Triple Vessels Ischemic Heart Disease with Viable Myocardial Tissues. Cardiology and Cardiovascular Research, 9(4), 131-136. https://doi.org/10.11648/j.ccr.20250904.13
ACS Style
Alauddin, M.; Sunny, M. S. A.; Rahman, K. M. A.; Hossain, N.; Ahmed, M., et al. Effect on Left Ventricular Ejection Fraction After off Pump Coronary Artery Bypass Grafting of Triple Vessels Ischemic Heart Disease with Viable Myocardial Tissues. Cardiol. Cardiovasc. Res. 2025, 9(4), 131-136. doi: 10.11648/j.ccr.20250904.13
AMA Style
Alauddin M, Sunny MSA, Rahman KMA, Hossain N, Ahmed M, et al. Effect on Left Ventricular Ejection Fraction After off Pump Coronary Artery Bypass Grafting of Triple Vessels Ischemic Heart Disease with Viable Myocardial Tissues. Cardiol Cardiovasc Res. 2025;9(4):131-136. doi: 10.11648/j.ccr.20250904.13
@article{10.11648/j.ccr.20250904.13,
author = {Md. Alauddin and Mohammad Samir Azam Sunny and Khan Mohammad Amanur Rahman and Nawrin Hossain and Marina Ahmed and Umme Habiba Rahman and Md. Mostafizur Rahman},
title = {Effect on Left Ventricular Ejection Fraction After off Pump Coronary Artery Bypass Grafting of Triple Vessels Ischemic Heart Disease with Viable Myocardial Tissues},
journal = {Cardiology and Cardiovascular Research},
volume = {9},
number = {4},
pages = {131-136},
doi = {10.11648/j.ccr.20250904.13},
url = {https://doi.org/10.11648/j.ccr.20250904.13},
eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20250904.13},
abstract = {Background: Patients with triple-vessel ischemic heart disease and reduced left ventricular ejection fraction (LVEF) present a high-risk surgical population. Off-pump coronary artery bypass grafting (OPCAB) has been proposed as a safe revascularization strategy with potential for functional recovery. This study aimed to evaluate changes in LVEF and perioperative outcomes following OPCAB in patients stratified by baseline LVEF. Methods: This descriptive cross-sectional study was conducted in the Department of Cardiac Surgery, Bangladesh Medical University, Dhaka, from September 2024 to August 2025. A total of 120 patients with angiographically confirmed triple-vessel ischemic heart disease and viable myocardium assessed by Dobutamine stress echocardiography underwent OPCAB. Patients were divided into four groups according to baseline LVEF: Group A (20–30%), Group B (31–40%), Group C (41–50%) and Group D (>51%). LVEF was measured by transthoracic echocardiography preoperatively, on the 7th postoperative day, at 1 month and at 3 months. Results: The mean age of the study population was 55.8 ± 7.0 years, with males comprising 68%. Progressive improvement in LVEF was observed in all groups. Group A showed the largest relative gain (25 ± 3% to 36 ± 5% at 3 months), with 83% achieving ≥5% improvement and 50% achieving ≥10%. Overall, 64% of patients improved by ≥5% and 28% by ≥10%. Perioperative mortality was low (0.8%), while postoperative myocardial infarction (3.3%), arrhythmias (11.7%), prolonged ICU stay (18.3%) and wound infection (3.3%) were observed, particularly among patients with lower baseline EF. Conclusion: OPCAB in patients with triple-vessel ischemic heart disease and viable myocardium is associated with significant improvement in LVEF, particularly in those with lower baseline EF and carries a low incidence of perioperative complications.},
year = {2025}
}
TY - JOUR T1 - Effect on Left Ventricular Ejection Fraction After off Pump Coronary Artery Bypass Grafting of Triple Vessels Ischemic Heart Disease with Viable Myocardial Tissues AU - Md. Alauddin AU - Mohammad Samir Azam Sunny AU - Khan Mohammad Amanur Rahman AU - Nawrin Hossain AU - Marina Ahmed AU - Umme Habiba Rahman AU - Md. Mostafizur Rahman Y1 - 2025/10/31 PY - 2025 N1 - https://doi.org/10.11648/j.ccr.20250904.13 DO - 10.11648/j.ccr.20250904.13 T2 - Cardiology and Cardiovascular Research JF - Cardiology and Cardiovascular Research JO - Cardiology and Cardiovascular Research SP - 131 EP - 136 PB - Science Publishing Group SN - 2578-8914 UR - https://doi.org/10.11648/j.ccr.20250904.13 AB - Background: Patients with triple-vessel ischemic heart disease and reduced left ventricular ejection fraction (LVEF) present a high-risk surgical population. Off-pump coronary artery bypass grafting (OPCAB) has been proposed as a safe revascularization strategy with potential for functional recovery. This study aimed to evaluate changes in LVEF and perioperative outcomes following OPCAB in patients stratified by baseline LVEF. Methods: This descriptive cross-sectional study was conducted in the Department of Cardiac Surgery, Bangladesh Medical University, Dhaka, from September 2024 to August 2025. A total of 120 patients with angiographically confirmed triple-vessel ischemic heart disease and viable myocardium assessed by Dobutamine stress echocardiography underwent OPCAB. Patients were divided into four groups according to baseline LVEF: Group A (20–30%), Group B (31–40%), Group C (41–50%) and Group D (>51%). LVEF was measured by transthoracic echocardiography preoperatively, on the 7th postoperative day, at 1 month and at 3 months. Results: The mean age of the study population was 55.8 ± 7.0 years, with males comprising 68%. Progressive improvement in LVEF was observed in all groups. Group A showed the largest relative gain (25 ± 3% to 36 ± 5% at 3 months), with 83% achieving ≥5% improvement and 50% achieving ≥10%. Overall, 64% of patients improved by ≥5% and 28% by ≥10%. Perioperative mortality was low (0.8%), while postoperative myocardial infarction (3.3%), arrhythmias (11.7%), prolonged ICU stay (18.3%) and wound infection (3.3%) were observed, particularly among patients with lower baseline EF. Conclusion: OPCAB in patients with triple-vessel ischemic heart disease and viable myocardium is associated with significant improvement in LVEF, particularly in those with lower baseline EF and carries a low incidence of perioperative complications. VL - 9 IS - 4 ER -