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Evolution of Heart Failure with Reduced Ejection Fraction in a Cardiology Clinic in Cotonou

Received: 9 October 2025     Accepted: 31 October 2025     Published: 9 December 2025
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Abstract

Introduction: Heart failure, the final stage of most heart diseases, is responsible for high mortality. The aim of this work was to study the evolutionary profile of heart failure with reduced ejection fraction (HFrEF) among patients followed at the University Cardiology Clinic of Cotonou. Material and Method: This was a descriptive, observational, longitudinal and analytical study conducted from January 2021 to June 2022. It included by exhaustive sampling patients who presented with HFrEF. Inclusion was made during post-hospitalization follow-up. The variables studied were clinical presentation, CHARLSON score summarizing the burden of comorbidities, mortality rate and number of re-hospitalizations. Results: A total of one hundred and thirteen (113) patients were included in the study. Mean age was 53.2 ± 17.3 years, with a sex ratio of 1.75. Dyspnea was stage III in 59.5% of patients and stage IV in 8.1%. The CHARLSON score was greater than or equal to 3 in 12.4% of cases. The re-hospitalization rate was 18.6%, and the one-year mortality rate was 33.6%. Factors associated with death included advanced age, left ventricular ejection fraction below 30% and a CHARLSON score greater than or equal to 3. Conclusion: HFrEF is a severe pathology associated with a poor prognosis. These findings underscore the critical need for early and aggressive management strategies, with the rigorous control of associated comorbidities.

Published in Cardiology and Cardiovascular Research (Volume 9, Issue 4)
DOI 10.11648/j.ccr.20250904.17
Page(s) 159-166
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2025. Published by Science Publishing Group

Keywords

Heart Failure, Mortality, Re-hospitalization

References
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Cite This Article
  • APA Style

    Sonou, D. J. A., Tchaniga, B., Tiomon, B., Agboton, B., Adeossi, A., et al. (2025). Evolution of Heart Failure with Reduced Ejection Fraction in a Cardiology Clinic in Cotonou. Cardiology and Cardiovascular Research, 9(4), 159-166. https://doi.org/10.11648/j.ccr.20250904.17

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    ACS Style

    Sonou, D. J. A.; Tchaniga, B.; Tiomon, B.; Agboton, B.; Adeossi, A., et al. Evolution of Heart Failure with Reduced Ejection Fraction in a Cardiology Clinic in Cotonou. Cardiol. Cardiovasc. Res. 2025, 9(4), 159-166. doi: 10.11648/j.ccr.20250904.17

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    AMA Style

    Sonou DJA, Tchaniga B, Tiomon B, Agboton B, Adeossi A, et al. Evolution of Heart Failure with Reduced Ejection Fraction in a Cardiology Clinic in Cotonou. Cardiol Cardiovasc Res. 2025;9(4):159-166. doi: 10.11648/j.ccr.20250904.17

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  • @article{10.11648/j.ccr.20250904.17,
      author = {Djidjoho Joël Arnaud Sonou and Baudouin Tchaniga and Baudouin Tiomon and Bruno Agboton and Armel Adeossi and Rineste Sagbohan and Witesse Houndjo and Ibrahim Gbadamassi and Marie Noëlle Tamekem and David Mawu-Kolo Bokodaho and Francis Agué Soummonni and David Dossou and Xavier Fadonougbo and Philippe Agbalika and Elodie Tondji and Murielle Hounkponou and Léopold Houétondji Codjo},
      title = {Evolution of Heart Failure with Reduced Ejection Fraction in a Cardiology Clinic in Cotonou},
      journal = {Cardiology and Cardiovascular Research},
      volume = {9},
      number = {4},
      pages = {159-166},
      doi = {10.11648/j.ccr.20250904.17},
      url = {https://doi.org/10.11648/j.ccr.20250904.17},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20250904.17},
      abstract = {Introduction: Heart failure, the final stage of most heart diseases, is responsible for high mortality. The aim of this work was to study the evolutionary profile of heart failure with reduced ejection fraction (HFrEF) among patients followed at the University Cardiology Clinic of Cotonou. Material and Method: This was a descriptive, observational, longitudinal and analytical study conducted from January 2021 to June 2022. It included by exhaustive sampling patients who presented with HFrEF. Inclusion was made during post-hospitalization follow-up. The variables studied were clinical presentation, CHARLSON score summarizing the burden of comorbidities, mortality rate and number of re-hospitalizations. Results: A total of one hundred and thirteen (113) patients were included in the study. Mean age was 53.2 ± 17.3 years, with a sex ratio of 1.75. Dyspnea was stage III in 59.5% of patients and stage IV in 8.1%. The CHARLSON score was greater than or equal to 3 in 12.4% of cases. The re-hospitalization rate was 18.6%, and the one-year mortality rate was 33.6%. Factors associated with death included advanced age, left ventricular ejection fraction below 30% and a CHARLSON score greater than or equal to 3. Conclusion: HFrEF is a severe pathology associated with a poor prognosis. These findings underscore the critical need for early and aggressive management strategies, with the rigorous control of associated comorbidities.},
     year = {2025}
    }
    

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  • TY  - JOUR
    T1  - Evolution of Heart Failure with Reduced Ejection Fraction in a Cardiology Clinic in Cotonou
    AU  - Djidjoho Joël Arnaud Sonou
    AU  - Baudouin Tchaniga
    AU  - Baudouin Tiomon
    AU  - Bruno Agboton
    AU  - Armel Adeossi
    AU  - Rineste Sagbohan
    AU  - Witesse Houndjo
    AU  - Ibrahim Gbadamassi
    AU  - Marie Noëlle Tamekem
    AU  - David Mawu-Kolo Bokodaho
    AU  - Francis Agué Soummonni
    AU  - David Dossou
    AU  - Xavier Fadonougbo
    AU  - Philippe Agbalika
    AU  - Elodie Tondji
    AU  - Murielle Hounkponou
    AU  - Léopold Houétondji Codjo
    Y1  - 2025/12/09
    PY  - 2025
    N1  - https://doi.org/10.11648/j.ccr.20250904.17
    DO  - 10.11648/j.ccr.20250904.17
    T2  - Cardiology and Cardiovascular Research
    JF  - Cardiology and Cardiovascular Research
    JO  - Cardiology and Cardiovascular Research
    SP  - 159
    EP  - 166
    PB  - Science Publishing Group
    SN  - 2578-8914
    UR  - https://doi.org/10.11648/j.ccr.20250904.17
    AB  - Introduction: Heart failure, the final stage of most heart diseases, is responsible for high mortality. The aim of this work was to study the evolutionary profile of heart failure with reduced ejection fraction (HFrEF) among patients followed at the University Cardiology Clinic of Cotonou. Material and Method: This was a descriptive, observational, longitudinal and analytical study conducted from January 2021 to June 2022. It included by exhaustive sampling patients who presented with HFrEF. Inclusion was made during post-hospitalization follow-up. The variables studied were clinical presentation, CHARLSON score summarizing the burden of comorbidities, mortality rate and number of re-hospitalizations. Results: A total of one hundred and thirteen (113) patients were included in the study. Mean age was 53.2 ± 17.3 years, with a sex ratio of 1.75. Dyspnea was stage III in 59.5% of patients and stage IV in 8.1%. The CHARLSON score was greater than or equal to 3 in 12.4% of cases. The re-hospitalization rate was 18.6%, and the one-year mortality rate was 33.6%. Factors associated with death included advanced age, left ventricular ejection fraction below 30% and a CHARLSON score greater than or equal to 3. Conclusion: HFrEF is a severe pathology associated with a poor prognosis. These findings underscore the critical need for early and aggressive management strategies, with the rigorous control of associated comorbidities.
    VL  - 9
    IS  - 4
    ER  - 

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Author Information
  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Nephrology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • University Cardiology Clinic, National Teaching Hospital Hubert Koutoukou Maga of Cotonou, Cotonou, Benin

  • Cardiology Department, Calavi International Hospital, Abomey-Calavi, Benin

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