@article{10.11648/j.ccr.20250904.18,
  author = {Owona Amalia and Nganou-Gnindjio Chris Nadege and Mbouombouo Jonas and Lom Bill and Mintom Pierre and Ebene Manon and Ndobo Valerie and Boombhi Jerome and Kuate Mfeukeu Liliane and Ndongo Amougou Sylvie Laure and Hamadou BA and Menanga Alain Patrick},
  title = {Prevalence of Hyponatremia Amongst Patients with Heart Failure in Two Sub-Saharan Hospitals: Cross-sectional Study},
  journal = {Cardiology and Cardiovascular Research},
  volume = {9},
  number = {4},
  pages = {167-171},
  doi = {10.11648/j.ccr.20250904.18},
  url = {https://doi.org/10.11648/j.ccr.20250904.18},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ccr.20250904.18},
  abstract = {Background: Hyponatremia is a very frequent abnormality amongst patients with Heart failure (HF) and significantly increases the morbidity and length of hospital stays amongst these patients. There is limited data on the epidemiology of this condition in sub-Saharan countries like Cameroon. This study therefore seeks to estimate the prevalence of hyponatremia amongst patients admitted for HF in 2 university hospitals in Cameroon. Methods: A hospital-based retrospective cross-sectional study was conducted in two University Hospital in Yaounde; Cameroon on patient files of patients admitted for HF from January 2021 to January 2022. A total of 107 participants were included using exhaustive sampling. Data were obtained from the patients’ medical records and analyzed using SPSS version 23.0. Frequencies were expressed as percentage (%) and continuous variables were presented as mean ± standard deviation. Comparison of categorical variables was done using the Chi-square tests. Results: A total of 184 patients were admitted for HF decompensations in the study period. Of these, 132 files were available but only 107 patient files met inclusion criteria. The female sex predominated in this study (55.1%) with a sex ratio (M/F) of 0.77. The majority of patients in this study were elderly patients with a mean age of 61.3±17.1 years and the age range of 70 years and above being the most frequent (31.8%). The prevalence of hyponatremia in this study was 32.7% dominated by mild hyponatremia (22.4%) followed by moderate (5.6%) and severe (2.8%) hyponatremia. The mean serum sodium level was 36.98 ± 5.24 mEq/l with extreme values of 122.0mEq/l and 148mEq/l. More than half of the participants in this study had a previous diagnosis of hypertension (53.3%) while 16.3% had diabetes mellitus. The most common etiologies for HF in our study were hypertensive cardiopathy (43.9%) and dilated cardiopathies (32.7%). Ischemic cardiopathies made up only 9.3% of etiologies in this study. 64.5% of participants were classified as NYHA class IV on admission. The predominant clinical manifestations at admission were dyspnea (92.5%) followed by pedal edema (76.6%) and pulmonary congestion (54.2%). One tenth of patients presented in a state of cardiogenic shock (10.3%). 45.8% of participants presented an anemia on complete blood count (Hb2). Conclusion: Hyponatremia is very frequent amongst patients admitted for HF affecting about a third of patients. Despite this high prevalence, the vast majority of cases are mild with very few patients presenting with severe hyponatremia.},
 year = {2025}
}

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TY  - JOUR
T1  - Prevalence of Hyponatremia Amongst Patients with Heart Failure in Two Sub-Saharan Hospitals: Cross-sectional Study
AU  - Owona Amalia
AU  - Nganou-Gnindjio Chris Nadege
AU  - Mbouombouo Jonas
AU  - Lom Bill
AU  - Mintom Pierre
AU  - Ebene Manon
AU  - Ndobo Valerie
AU  - Boombhi Jerome
AU  - Kuate Mfeukeu Liliane
AU  - Ndongo Amougou Sylvie Laure
AU  - Hamadou BA
AU  - Menanga Alain Patrick
Y1  - 2025/12/09
PY  - 2025
N1  - https://doi.org/10.11648/j.ccr.20250904.18
DO  - 10.11648/j.ccr.20250904.18
T2  - Cardiology and Cardiovascular Research
JF  - Cardiology and Cardiovascular Research
JO  - Cardiology and Cardiovascular Research
SP  - 167
EP  - 171
PB  - Science Publishing Group
SN  - 2578-8914
UR  - https://doi.org/10.11648/j.ccr.20250904.18
AB  - Background: Hyponatremia is a very frequent abnormality amongst patients with Heart failure (HF) and significantly increases the morbidity and length of hospital stays amongst these patients. There is limited data on the epidemiology of this condition in sub-Saharan countries like Cameroon. This study therefore seeks to estimate the prevalence of hyponatremia amongst patients admitted for HF in 2 university hospitals in Cameroon. Methods: A hospital-based retrospective cross-sectional study was conducted in two University Hospital in Yaounde; Cameroon on patient files of patients admitted for HF from January 2021 to January 2022. A total of 107 participants were included using exhaustive sampling. Data were obtained from the patients’ medical records and analyzed using SPSS version 23.0. Frequencies were expressed as percentage (%) and continuous variables were presented as mean ± standard deviation. Comparison of categorical variables was done using the Chi-square tests. Results: A total of 184 patients were admitted for HF decompensations in the study period. Of these, 132 files were available but only 107 patient files met inclusion criteria. The female sex predominated in this study (55.1%) with a sex ratio (M/F) of 0.77. The majority of patients in this study were elderly patients with a mean age of 61.3±17.1 years and the age range of 70 years and above being the most frequent (31.8%). The prevalence of hyponatremia in this study was 32.7% dominated by mild hyponatremia (22.4%) followed by moderate (5.6%) and severe (2.8%) hyponatremia. The mean serum sodium level was 36.98 ± 5.24 mEq/l with extreme values of 122.0mEq/l and 148mEq/l. More than half of the participants in this study had a previous diagnosis of hypertension (53.3%) while 16.3% had diabetes mellitus. The most common etiologies for HF in our study were hypertensive cardiopathy (43.9%) and dilated cardiopathies (32.7%). Ischemic cardiopathies made up only 9.3% of etiologies in this study. 64.5% of participants were classified as NYHA class IV on admission. The predominant clinical manifestations at admission were dyspnea (92.5%) followed by pedal edema (76.6%) and pulmonary congestion (54.2%). One tenth of patients presented in a state of cardiogenic shock (10.3%). 45.8% of participants presented an anemia on complete blood count (Hb2). Conclusion: Hyponatremia is very frequent amongst patients admitted for HF affecting about a third of patients. Despite this high prevalence, the vast majority of cases are mild with very few patients presenting with severe hyponatremia.
VL  - 9
IS  - 4
ER  - 

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